Type de poste: 
CDD
Date de début: 
as soon as possible
Durée: 
1 year contract that can be reniewed for up to 3 years
Ville: 
Paris
Nom du contact: 
Isabelle Audo and Christina Zeitz
Mail du contact: 
isabelle.audo@inserm.fr
Missions: 
Our genetic team is dedicated to deciphering underlying gene defect and pathogenic mechanisms in inherited retinal diseases applying next-generation sequencing tools. We are looking for an engineer or a postdoctoral fellow in bioinformatics to get involve in these ongoing projects (NGS, WES, WGS, RNAseq). The applicant will develop and optimize analytic algorithms to extract significant variants from data generated by these techniques applying homozygosity mapping, linkage, CNV analysis and cross correlate high throughput data with transcriptomic data generated from RNAseq performed on patients' iPS cell lines or animal models as well as available transcriptomic databases.
Connaissances: 
Master or PhD in bioinformatics with a strong knowledge in bioinfomatic analysis applied to NGS/WES/WGS/RNAseq.
The ideal candidate should be enthusiastic, highly motivated, happy to communicate and animated with team spirit, independent with good skills in biology, computer science and a previous experience in high throughput sequencing analysis. The candidate should have good knowledge of basic informatic and bioinformatic environment (i.e. LINUX, programming language (eg PHYTHON), Galaxy or equivalent, R).
A good level of written and oral English is required.
Spécificités: 
The initial contract will be for 1 year which can be prolonged for up to 3 years.
Submit a CV, including description of research interests, experience and contact information for at least two references by e-mail to isabelle.audo@inserm.fr and christina.zeitz@inserm.fr
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